Abstract

A simple and sensitive spectrophotometric method for the determination of nimodipine in bulk and pharmaceutical dosage forms is described. The method is based on diazotisation of reduced nimodipine with nitrous acid followed by its coupling with alpha-naphthylamine to form a pink colored chromogen with an absorption maximum of 550 nm. The color obeyed Beer's law in the concentration range of 2-12 mug/ml