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Abstract
Visible spectrophotometric estimation of aceclofenac and indapamide from tablets using folin-ciocalteu reagent
Author(s): I Singhvi1, Anju Goyal2
1 Department of Pharmaceutical Sciences, M. L. Sukhadia University, Udaipur-313 001, India 2 B. N. P. G. College of Pharmacy, Udaipur-313 002, India
Correspondence Address:
I Singhvi Department of Pharmaceutical Sciences, M. L. Sukhadia University, Udaipur-313 001 India E-mail: indrajeet_s@yahoo.com
1 Department of Pharmaceutical Sciences, M. L. Sukhadia University, Udaipur-313 001, India 2 B. N. P. G. College of Pharmacy, Udaipur-313 002, India
Correspondence Address:
I Singhvi Department of Pharmaceutical Sciences, M. L. Sukhadia University, Udaipur-313 001 India E-mail: indrajeet_s@yahoo.com
Two simple, accurate, fast and economical methods have been developed for the quantitative estimation of aceclofenac and indapamide from their respective tablet formulation using Folin-Ciocalteu reagent. Aceclofenac forms a blue colored chromogen with the reagent, which shows absorbance maxima at 642.6 nm and linearity in the concentration range of 80-160 µg/ml of drug. Indapamide forms a green colored chromogen with the reagent, which shows absorbance maxima at 783.2 nm and linearity in the concentration range of 2-12 µg/ml of drug. The results of analysis for both the methods were validated statistically and by recovery studies.
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