Abstract

Coronavirus disease-19 outbreak has caused worldwide health and economic crisis. The disease resulting in massive death all over the globe and pandemic has been considered it as the greatest crises. Few effective medications for the treatment of coronavirus disease-19 individuals have developed so far, while several herbal therapeutic preparations might be helpful against coronavirus disease-19 or the associated complications. Thymoquinone is one of the biological compounds which have been derived to show powerful therapeutic potential against various complications associated with coronavirus disease-19 infection. Nigella sativa seeds (black seeds) contain thymoquinone, an active ingredient which has been reported to have anti-inflammatory, anti-cancer and antioxidant effects. In this review, we address the multifunctional therapeutic potential of thymoquinone specifically against coronavirus disease-19, including its efficacy towards pathoanomalies and multi-organ complications associated with coronavirus disease-19 infections.