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Abstract
Timed-release noscapine microcapsules.
Author(s): R Narsimhan, VD Labhasetwar, CL Lakhotia, AK Dorle
Dept. of Pharmaceutical Sciences, Nagpur University Campus, Nagpur-440 010,
Correspondence Address:
R Narsimhan Dept. of Pharmaceutical Sciences, Nagpur University Campus, Nagpur-440 010
Dept. of Pharmaceutical Sciences, Nagpur University Campus, Nagpur-440 010,
Correspondence Address:
R Narsimhan Dept. of Pharmaceutical Sciences, Nagpur University Campus, Nagpur-440 010
Noscapine was formulated into timed-release microcapsules so as to have the effect of the drug for 8 hours. Nonpariel seeds were chosen as the drug carrier and Eudragit-L and Eudragit-S as coating materials. Uncoated and 12-coated microcapsules were mixed and filled in hard gelatin capsule for the final dosage form.
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