Abstract

In order to explore the harm caused by Escherichia coli infection to puerperium, and to propose effective and feasible treatment plan, 68 women who are born in hospital and have Escherichia coli infection during puerperium are selected as research objects. According to different treatment methods, they are divided into observation group and experimental group, with 34 cases in each group. The observation group is treated with levofloxacin hydrochloride. The experimental group is treated with cefazolin and levofloxacin hydrochloride. The time of disappearance, adverse reactions and clinical efficacy are compared between the two groups. Studies have found that women infected with Escherichia coli during puerperal period can cause uterine tenderness, anal pain, abnormal lochia, breast tenderness, etc., and timely anti-infective treatment is needed. The total effective rate of maternal treatment in the experimental group is 94.1%, and the total effective rate of maternal treatment in the observation group is 70.6%. The difference between the two groups is statistically significant (P < 0.05). The disappearance time of lower abdominal pain, anal pain and abnormal lochia in the experimental group is shorter than that in the observation group, and the difference is statistically significant (P < 0.05). The incidence of adverse reactions in the experimental group is 8.8%, which is significantly lower than that in the control group (35.3%). The difference is statistically significant (P < 0.05). The effect of cefazolin combined with levofloxacin hydrochloride on the maternal treatment of Escherichia coli in the puerperium period is significant. The clinical symptoms of the patients are obviously improved, and the adverse reactions are less, which is worthy of clinical application.