Abstract

The effect of dezocine combined with oxycodone on the pain score (numerical rating scale score) of patients with severe cancer pain caused by bone metastasis of advanced lung cancer was analyzed. The patients were divided into two groups with 50 cases in each group. The control group was given intramuscular injection of dezocine for analgesia and the observation group was given oral oxycodone hydrochloride controlled release tablets on the basis of intramuscular injection of dezocine for analgesia. The pain relief rate and analgesic efficiency of the observation group were better than those of the control group and the numerical rating scale score was lower than that of the control group. The number of burst pain in the observation group was less than that in the control group, the stable time of first pain control was shorter than that in the control group and the increase time of 24 h sleep was longer than that in the control group, with statistical significance. After treatment, the overall health status score, functional score and symptomatic score of the two groups were significantly higher than those before treatment. Dezocine combined with oxycodone in the treatment of severe cancer pain in advanced lung cancer with bone metastasis can effectively relieve pain, regulate the expression of pain factors and improve the quality of life.