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Abstract
Synthesis, UV/Vis and Fluorescence studies of Naphthoquinone Pyridyl Tetrazole-based Chemical Probe
Author(s): K. Balakrishna, D. Vijaya Lakshmi, S. Mustafa*, K. S. Reddy and T. K. Ghorpade1
Department of Chemistry, GITAM University, Hyderabad campus, Rudraram, Hyderabad-502 329, 1Polymer Science and Technology Centre, Naval Materials Research Laboratory, Ambernath, Maharastra-421 506, India
Correspondence Address:
Department of Chemistry, GITAM University, Hyderabad campus, Rudraram, Hyderabad-502 329, India, E-mail: mustaff_02@yahoo.co.in
Department of Chemistry, GITAM University, Hyderabad campus, Rudraram, Hyderabad-502 329, 1Polymer Science and Technology Centre, Naval Materials Research Laboratory, Ambernath, Maharastra-421 506, India
Correspondence Address:
Department of Chemistry, GITAM University, Hyderabad campus, Rudraram, Hyderabad-502 329, India, E-mail: mustaff_02@yahoo.co.in
2-(dimethylamino)-3-(5-(pyridin-2-yl)-1H-tetrazol-1-yl)naphthalene-1,4-dione (2) has been synthesized. The UV/Vis studies of 2-(dimethylamino)-3-(5-(pyridin-2-yl)-1H-tetrazol-1-yl)naphthalene-1,4-dione (2) with different metal ions were performed in aqueous dimethylformamide and were correlated with fluorescence studies of the same. The compound showed higher selectivity and sensitivity for Zn2+ ions. Thus this compound could be utilized as a turn-on probe for fluorescent imaging of Zn2+ ions in living cells.
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