All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.
Abstract
Synthesis and pharmacological evaluation of (6-substituted 4-Oxo-4 H -chromene-3 yl) methyl N-substituted aminoacetates
Author(s): Asmita Gajbhiye1, V Mallareddy2, G Achaiah1
1Medicinal Chemistry Research Lab, University College of Pharmaceutical Sciences, Kakatiya University, India 2Vaagdevi College of Pharmacy, Ram Nagar, Kakatiya University, India
Correspondence Address:
G Achaiah, Medicinal Chemistry Research Lab, University College of Pharmaceutical Sciences, Kakatiya University, India, E-mail: achaiah_g@yahoo.co.in
1Medicinal Chemistry Research Lab, University College of Pharmaceutical Sciences, Kakatiya University, India 2Vaagdevi College of Pharmacy, Ram Nagar, Kakatiya University, India
Correspondence Address:
G Achaiah, Medicinal Chemistry Research Lab, University College of Pharmaceutical Sciences, Kakatiya University, India, E-mail: achaiah_g@yahoo.co.in
A series of the title compounds were synthesized and characterized by spectral data. All the compounds were evaluated for in vitro antihistaminic activity by inhibition of isotonic contractions induced by histamine on isolated guinea pig ileum and the compound 6-k showed significant activity. A few compounds have also been screened for in vivo bronchodilatory activity. These compounds exhibited significant protection against histamine-induced convulsions in guinea pig at the dose of 50 µmol.
Awek melayu tak lawa, indian desi girl was fucked by stepbrother, desi aunt xxx, english xxx, xxx video com, hindi story sex video
Full-Text | PDF
