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Abstract
Synthesis And Evaluation Of Some Novel 2-Mercapto-3-(Substitutedmethylamino)Quinazolin-4(3H)-Ones As Analgesic, Antiinflammatory And Antibacterial Agents
Author(s): V Alagarsamy, U. S Pathak, R. K Goyal
In view of the potent analgesic, antiinflammatory and antimicrobial activities exhibited by quinazolin-4(3H)-ones, a series of novel 2-mercapto-3-(substitutedmethyl amino)quinazolin-4(3H)-ones have been synthesized. When these compounds were evaluated for their analgesic, antiinflammatory and antibacterial activities, the compounds, I, II, Ill, IV, V and X exhibited comparable analgesic activity with the standard diclofenac sodium and it was found to be significant as compared to control.
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