All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.
Abstract
Synthesis and antiulcer activity studies of 2-(1'-iminothioimido substituted)-1'-substituted phenylbenzoic acids
Author(s): BB Subudhi, D Bhatta, PK Panda, P Mishra, D Pradhan
University Department of Pharmaceutical Sciences, Utkal University, Vanivihar, Bhubaneshwar-751 004, India
Correspondence Address:
B B Subudhi University Department of Pharmaceutical Sciences, Utkal University, Vanivihar, Bhubaneshwar-751 004 India E-mail: bharatsubudhi@yahoo.co.in
University Department of Pharmaceutical Sciences, Utkal University, Vanivihar, Bhubaneshwar-751 004, India
Correspondence Address:
B B Subudhi University Department of Pharmaceutical Sciences, Utkal University, Vanivihar, Bhubaneshwar-751 004 India E-mail: bharatsubudhi@yahoo.co.in
Certain 2-(1'-iminothioimido substituted)-1'-substituted phenybenzoic acids (P 1-9 ) were synthesized by reaction of phthalic anhydride with benzotriazole, 2-mercapto benzothiazole and 2-p-amino phenyl benzimidazole, respectively (A 1-3 ) followed by imine formation with Schiff bases of thiourea with salicylaldehyde, furfuraldehyde and 1-phenyl-3-methyl-5-pyrazolone. Antiulcer activity was evaluated using reduction in total acidity, free acidity and ulcer index as parameters. Compounds P 3 , P 6 , P 7 and P 9 (100 mg/kg) showed significant (P<0.001) antiulcer action compared to control and omeprazole (40 mg/kg).
indian couple sex, indian sex, xxx video hd full hd, hot sexy video, rajasthani bf video, kajal agarwal sex
Full-Text | PDF
