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Abstract
Synthesis and antiinflammatory activity of substituted (2-oxochromen-3-yl)benzamides
Author(s): V Maddi1, SN Mamledesai1, D Satyanarayana2, S Swamy3
1 Department of Pharmaceutical Chemistry, K. L. E. S's College of Pharmacy, Hubli, India 2 Department of Pharmaceutical Chemistry, N. G. S. M. Institute of Pharmaceutical Sciences, Mangalore, India 3 Department of Pharmacology, Sree Siddaganga College of Pharmacy, Tumakur, India
Correspondence Address:
V Maddi Department of Pharmaceutical Chemistry, K. L. E. S's College of Pharmacy, Vidyanagar, Hubli - 580 031 India E-mail: veeresh_m@rediffmail.com
1 Department of Pharmaceutical Chemistry, K. L. E. S's College of Pharmacy, Hubli, India 2 Department of Pharmaceutical Chemistry, N. G. S. M. Institute of Pharmaceutical Sciences, Mangalore, India 3 Department of Pharmacology, Sree Siddaganga College of Pharmacy, Tumakur, India
Correspondence Address:
V Maddi Department of Pharmaceutical Chemistry, K. L. E. S's College of Pharmacy, Vidyanagar, Hubli - 580 031 India E-mail: veeresh_m@rediffmail.com
The title compounds were synthesized by condensing 3-aminocoumarin with substituted aromatic acid chlorides. The acid chlorides were prepared from different substituted aromatic carboxylic acids and thionyl chloride. The structures of the compounds were confirmed by IR, NMR spectral data and elemental analysis. The title compounds were found to possess significant anti-inflammatory and analgesic activities.
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