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Abstract

Spectrophotometric estimation of acyclovir in pharmaceutical dosage forms

Author(s): Preeti Gandhi, Nilofar Momin, Sudha Kharade, NP Konapure, BS Kuchekar
Government College of Pharmacy, Vidya Nagar, Karad-415 124, India

Correspondence Address:
B S Kuchekar Government College of Pharmacy, Vidya Nagar, Karad-415 124 India E-mail: bskuchekar2000@yahoo.com


A simple, sensitive, rapid, accurate and precise spectrophotometric method has been developed for estimation of acyclovir in bulk and pharmaceutical dosage forms. Acyclovir shows maximum absorbance at 253 nm with molar absortivity of 1.3733 ×104 l/mol×cm Beer's law was obeyed in the concentration range of 2-20 µg/ml. Results of the analysis were validated statistically and by recovery studies.

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