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Abstract
Soyabean powder as a novel diluent in tablet formulation of simvastatin
Author(s): G Swami, Khushboo Gupta, KM Kymonil, Shubhini Saraf
Department of Pharmaceutics, Faculty of Pharmacy, Babu Banarasi Das National Institute of Technology and Management, Lucknow - 227 105, India
Correspondence Address:
G Swami Department of Pharmaceutics, Faculty of Pharmacy, Babu Banarasi Das National Institute of Technology and Management, Lucknow - 227 105 India E-mail: gauravswam@gmail.com
Department of Pharmaceutics, Faculty of Pharmacy, Babu Banarasi Das National Institute of Technology and Management, Lucknow - 227 105, India
Correspondence Address:
G Swami Department of Pharmaceutics, Faculty of Pharmacy, Babu Banarasi Das National Institute of Technology and Management, Lucknow - 227 105 India E-mail: gauravswam@gmail.com
The present research paper introduces soyabean nuggets powder, as a novel excipient with nutraceutical value for tablets containing cholesterol lowering drug, simvastatin. Experiments were carried out to evaluate the suitability of soyabean nuggets powder as a diluent by incorporating in tablet formulation of simvastatin. The formulation was compared with the marketed product to determine its relative efficacy. Soyabean nuggets powder was found to be a promising diluent for tablets for both pharmaceutical and nutraceutical purposes. Simavastatin soya tablet showed acceptable pharmacotechnical properties and assay requirement.
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