All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Abstract

Simultaneous HPLC Estimation Of Levonorgestrel And Ethinylestradiol From Tablets

Author(s): S Durga Prasad, G Changala Reddy, P. S. S Prasad, K Mukkanti

The present work describes a simple reverse phase HPLC method for the determination of levonorgestrel and ethinylestradiol from tablet formulations. The determination was carried out on a Hypersil, ODS, C-18 (150×4.6mm, 5 micron) column using a mobile phase of acetonitrile/ water (42:58). The flow rate and runtime were 2.2 ml/min and 7 min, respectively. The eluent was monitored at 210 nm. The method was found to be reproducible, with good resolution between levonorgestrel and ethinylestradiol. The detector response was found to be linear in the concentration range of 10-50 ppm for levonorgestrel and 2-10 ppm for ethinylestradiol.

PDF

 
 
Google scholar citation report
Citations : 69022

Indian Journal of Pharmaceutical Sciences received 69022 citations as per google scholar report