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Abstract
Reverse phase high performance liquid chromatographic determination of rabiprazole in tablet dosage form
Author(s): MS Palled, M Chatter, PNM Rajesh, AR Bhat
Department of Pharmaceutical Analysis, K. L. E. S's College of Pharmacy, Belgaum-590 010, India
Correspondence Address:
A R Bhat Department of Pharmaceutical Analysis, K. L. E. S's College of Pharmacy, Belgaum-590 010 India E-mail: anilchandrabhat@yahoo.com
Department of Pharmaceutical Analysis, K. L. E. S's College of Pharmacy, Belgaum-590 010, India
Correspondence Address:
A R Bhat Department of Pharmaceutical Analysis, K. L. E. S's College of Pharmacy, Belgaum-590 010 India E-mail: anilchandrabhat@yahoo.com
A simple, economical, fast, and precise reverse phase high performance liquid chromatographic method has been developed for the determination of rabiprazole in tablet dosage form. A C 18 Hypersil (5 micron 25 cm×4.6 mm) column from Thermo, in isocratic mode with mobile phase acetonitrile:phosphate buffer:methanol(50:40:10) The flow rate is 1.4 ml/min, and effluent was monitored at 232 nm.
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