Abstract
Recently Adopted Synthetic Approaches to Pyridine and Analogs: A Review
Department of Pharmaceutical Chemistry, Noida Institute of Engineering and Technology (Pharmacy Institute), Greater Noida, Uttar Pradesh 201310, 1Center for Global Health Research, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu 600077, 2One Health Centre, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education, Wardha, Maharashtra 442005, India
Correspondence Address:
R. Kumar, Department of Pharmaceutical Chemistry, Noida Institute of Engineering and Technology (Pharmacy Institute), Greater Noida, Uttar Pradesh 201310, India, E-mail: mpharm.rajnish@gmail.com
On basis of various research reports, pyridine was found to possess a wide spectrum of pharmacological activities along with many other industrial applications. Because of its diverse applications, pyridine moiety is the centre of attraction for researchers and a large number of patents have been granted focusing on it. Several synthetic protocols such as cyclo-condensation, cyclization, cycloaddition, electrolysis, etc., were used by researchers to synthesize pyridine and analogs. Each synthetic protocol has its merits and demerits and required several types of reagents, catalysts and reaction conditions. So, there is always a need for careful analysis of reported synthetic protocols whenever researchers like to initiate research consisting of the synthesis of pyridine and its analogs.
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