All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.
Abstract
Preparation and evaluation of sustained release nimesulide microspheres prepared from sodium alginate.
Author(s): VB Patil, VB Pokharkar
Department of Pharmaceutics, Bharati Vidyapeeth's Poona College of Pharmacy and Research Centre, Erandwane, Pune-411038
Department of Pharmaceutics, Bharati Vidyapeeth's Poona College of Pharmacy and Research Centre, Erandwane, Pune-411038
Correspondence Address:
V B Patil Department of Pharmaceutics, Bharati Vidyapeeth's Poona College of Pharmacy and Research Centre, Erandwane, Pune-411038
Department of Pharmaceutics, Bharati Vidyapeeth's Poona College of Pharmacy and Research Centre, Erandwane, Pune-411038
Correspondence Address:
V B Patil Department of Pharmaceutics, Bharati Vidyapeeth's Poona College of Pharmacy and Research Centre, Erandwane, Pune-411038
Nimesulide-loaded calcium alginate beads were prepared. In this investigation, a 2(3) full factorial design was used to study the joint influence of three variables, the polyemer concentration (X(1), the drug concerntration (X(2) and the cross-linker (calcium chloride) concentration (X(3), on various dependent variables like per cent entrapment, sphericity, particle size and amount of drug released during the initial (t=60 min) and final stages (t=360 min) of release. A statistical model with a significant interaction term is obtained to predict the results. The drug release mechanisms from microspheres were studied using the Peppas equation.
sex video, chudai hindi video, indian sexy couple, riya singh web series nude, Indonesian nurse sex scandal, hijabi girl painefull sex hindi audio hd
PDF
