Abstract
Pharmacological review on Centella asiatica: A potential herbal cure-all
1Department of Pharmacology, Maliba Pharmacy College, Bardoli-394 350, India 2Department of Pharmacology, Institute of Pharmacy, Nirma University (NU), Ahmedabad-382 481, India
Correspondence Address:
Kashmira J Gohil Department of Pharmacology, Maliba Pharmacy College, Bardoli-394 350 India E-mail: tokjgohil@yahoo.com
In recent times, focus on plant research has increased all over the world. Centella asiatica is an important medicinal herb that is widely used in the orient and is becoming popular in the West. Triterpenoid, saponins, the primary constituents of Centella asiatica are manly believed to be responsible for its wide therapeutic actions. Apart from wound healing, the herb is recommended for the treatment of various skin conditions such as leprosy, lupus, varicose ulcers, eczema, psoriasis, diarrhoea, fever, amenorrhea, diseases of the female genitourinary tract and also for relieving anxiety and improving cognition. The present review attempts to provide comprehensive information on pharmacology, mechanisms of action, various preclinical and clinical studies, safety precautions and current research prospects of the herb. At the same time, studies to evaluate the likelihood of interactions with drugs and herbs on simultaneous use, which is imperative for optimal and safe utilization of the herb, are discussed.