Abstract
Pharmacological Evaluation of Different Extracts of Forsskaolea tenacissima
Department of Botany, University of Hazara, Pakistan, Institute of Biotechnology and Genetic Engineering, University of Agriculture, Peshawar KPK, Pakistan
Correspondence Address:
Institute of Biotechnology and Genetic Engineering, University of Agriculture, Peshawar KPK, Pakistan E-mail: jehanbakht@yahoo.co.uk
The current research work was carried out to investigate the antimicrobial, antinociceptive and antipyretic activities of different solvent extracts of Forsskaolea tenacissima. This investigation revealed that ethyl acetate extract exerted maximum inhibition (56%) of the growth of Providencia mirabilis and 48% of Aspergillus fumigatus. Penecillium was the most resistant fungi and was unaffected by any extracts. The analgesic activity of these extracts at a dose of 150 mg/kg increased the reaction time after 60, 90, 120 and 180 min compared to the initial latency as well as that of control group in the hot plate method. The number of writhes recorded after 150 mg/kg extract were comparatively lower (56±3.74) than that of normal saline group (76±4.15) in acetic acid-induced writhing test. The antipyretic effect of the plant extracts at 300 mg/kg was comparable with normal saline.
