All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.
Abstract
Microwave Assisted Synthesis, AntiHIV, And AntiYFV Activities Of Schiff Bases Of N-HY-Droxy-N1-Aminoguanidine Tosylate
Author(s): D Sriram, P Yogeeswari, T. G Ashok Kumar
The microwave-assisted syntheses of N-hydroxy-N1-aminoguanidines (S1-S8) starting from thiosemicarbazide are reported herein. These derivatives were evaluated against infection by the human immunodeficiency virus type-1 using human T4 lymphocyte cell line and yellow fever virus strain 17D activity in Vero cells. Compound 1-(4'-chlorobenzylidene) amino-3-hydroxy guanidine (S3) showed maximum percentage protection of 43.68% against HIV-1 induced cytopathogenicity. Compound S3 was also found to be the most active compound against YFV with EC50 of 2.5 μM, and CC50 of more than 100 μM when compared to ribavirin.
desi sex video, riya singh web series nude, desi xxx, www qorno com, new xxx video, indian couple sex
PDF
