Abstract

Juglans regia L. is a wonder nut widely used as functional food owing to its multi-nutritional qualities. It is generally found in Southeast Europe extending towards the Himalayas and Southwest China. This historical plant is extensively used ethno-medicinally in the treatment of digestive, respiratory, cardiovascular and skin diseases. Its seeds are highly proteinaceous and polyphenolic containing triacylglycerol-rich oil especially mono and polyunsaturated fatty acids. The diverse lipid profile of the walnut has attracted the researchers of the decade towards scientific validation of its traditional aspects and isolation of important chemical compounds for improving human health. The present review comprehends the ameliorative effect of Juglans regia on various chronic diseases including cancer, gut dysbiosis, cardiovascular and neurodegeneration concerning its specific chemical profile.