Abstract

Formulation of ayurvedic powder preparations into tablets may increase dosage uniformity. Application of direct compression method to ayurvedic preparations can be regarded as a major advance. In the present study, dispersible tablets of panchagni lavana were prepared by direct compression method. Panchagni lavana was subjected to preformulation studies to test the suitability of direct compression method and appropriate formulations were developed. These formulations were further evaluated for hardness, friability, weight variation, uniformity of dispersion, disintegration test and stability studies. Attempts were made to get minimum possible disintegration time by varying the concentrations of sodium starch glycolate and starch. It was found that, use of mixture of both the disintegrating agents was highly useful in the formulation of dispersible tablets of panchagni lavana. The study further revealed the usefulness of direct compression method to formulate dispersible tablets of ayurvedic preparations.