Abstract
Exploring the Curative Effects of Anti-Human Papillomavirus Protein Dressing for High-Risk Human Papillomavirus Infection
Department of Oncology, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin’s Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin 300060, 1Department of Gynaecology, Tianjin First Center Hospital, Tianjin 300384, 2Department of Gynecology, The Fourth Hospital of Medical University of Hebei, Shijiazhuang, Hebei Province 050000, China
Correspondence Address:
Jing Ma, Department of Gynecology, The Fourth Hospital of Medical University of Hebei, Shijiazhuang, Hebei Province 050000, China, E-mail: mjfck@163.com
To explore the clinical effects of innovative anti-human papillomavirus biological protein dressing (Luke duokang) for high-risk human papillomavirus infection was the objective of this study. We collected the clinical information of 220 persistent high-risk human papillomavirus infection patients who were randomly divided into 2 groups according to their conditions (anti-human papillomavirus protein dressing and control groups) each with 110 individuals (n=110). Anti-human papillomavirus protein dressings group was using the one from Luke duokang antibody while the control group did not use any vaginal medication. Thin-layer cytology and human papillomavirus-deoxyribonucleic acid were re-examined after 3 mo of drug withdrawal. At the same time, the levels of interleukin-6, 8 and 17 were analyzed. Further, tumor necrosis factor-alpha and C-reactive protein were also measured by enzyme-linked immunosorbent assay. Respectively, white blood cells, neutrophils, lymphocytes, platelets, red blood cells, fibrinogen, D-dimer, total cholesterol, low and high density lipoproteins, triglycerides, n-terminal pro B type natriuretic peptide, creatinine, aspartate aminotransferase and alanine aminotransferase were also examined. Negative conversion rate of patients in the anti-human papillomavirus biological protein dressing group was 54.5 % (60/110), while the control group was 20 % (22/110). After using anti-human papillomavirus biological protein dressing, the expression level of inflammatory factors in the treatment group was significantly reduced, compared with the control group. Meanwhile, the expression levels of white blood cells, lymphocytes and alanine aminotransferase showed different patterns between the two groups (p<0.05). The incidence of adverse reactions in the antihuman papillomavirus biological protein dressing was similar to that in the control group. Anti-human papillomavirus biological protein dressing (Luke duokang) has achieved effective results in controlling highrisk human papillomavirus infection and protecting patients.
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