Abstract

To observe the effect of modified Wendan decoction on serological indicators in elderly patients with chronic cholecystitis of damp-heat syndrome in liver and gallbladder, and to evaluate the safety of this treatment regimen. A total of 60 elderly patients with chronic cholecystitis of damp-heat syndrome in liver and gallbladder admitted to our hospital from March 1st 2024 to May 31st 2024 were selected and evenly assigned to the control group (n=30) and the observation group (n=30) using the envelope method. The control group was treated with anti-inflammatory and gallbladder-stimulating tablets, while the observation group received modified Wendan decoction in addition to the treatment given to the control group. Each course of treatment lasted for 2 w, and both groups were treated for 2 courses. After the 2 courses, changes in serum inflammatory factor levels and immune function indices were observed in both groups. The comprehensive efficacy and safety of the two groups were evaluated based on the traditional Chinese medicine syndrome scores and color Doppler ultrasonography findings. After receiving 2 courses of treatment, the treatment regimen combining modified Wendan decoction and anti-inflammatory and gallbladder-stimulating tablets could effectively alleviate clinical symptoms, improve gallbladder function, and significantly enhance the clinical comprehensive efficacy. This treatment regimen did not cause significant damage to liver and kidney function, had high safety, and could control the inflammatory response in patients with chronic cholecystitis, providing an effective conservative treatment option for elderly patients with chronic cholecystitis of damp-heat syndrome in liver and gallbladder.