Abstract

To explore the clinical efficacy and safety of fumigation with Dibazol eye drops in the treatment of juvenile middle and low myopia. From January 2019 to January 2020, a total of 158 adolescent patients with moderate and low myopia were randomly divided into control group and observation group, with 79 cases in each group. The observation group was treated with ultrasonic atomization fumigation of 10 times diluted Dibazol eye drops, once a day. The patients in the control group were treated with Dibazol eye drops once a day for 30 d. The uncorrected visual acuity and best corrected visual acuity of the control group and the observation group were measured before and after treatment. The diopter and astigmatism of the two groups were detected by comprehensive refractometer. The therapeutic effect and adverse reactions of the two groups were compared after treatment. The total effective rate of the observation group was 75.95 %, which was significantly higher than 56.96 % of the control group (p<0.05). The uncorrected visual acuity and best corrected visual acuity of the two groups after treatment were higher than those before treatment (p<0.05), and the uncorrected visual acuity of the observation group after treatment was higher than that of the control group (p<0.05). The diopter of the two groups after treatment was higher than that before treatment (p<0.05) and the diopter of the observation group after treatment was significantly better than that of the control group (p<0.05). After treatment, the astigmatism of the observation group was lower than that before treatment, the difference was statistically significant (p<0.05), but there was no significant difference in the astigmatism of the control group before and after treatment (p>0.05). After treatment, there was no significant difference in astigmatism between the observation group and the control group (p>0.05). The incidence of eye irritation in the observation group was 2.53 %, which significantly alleviated the incidence of adverse reactions (p<0.05). The total adverse reaction rate of the observation group was 6.33 %, which was significantly lower than 17.72 % of the control group (p<0.05). Compared with eye drops, atomization fumigation of Dibazol eye drops can significantly improve the uncorrected visual acuity, improve the diopter after mydriasis, and reduce the incidence of eye irritation and eye fever, which is a potential treatment for myopia.