Abstract

Endophytes, which live asymptomatically within the healthy tissues of the host plant, have attracted researchers due to their massive bioactive potential. Some co-existing endophytes and their host plants have developed a unique interaction through time, which influences the creation of metabolic products in plants and thus the quality and amount of crude pharmaceuticals obtained from medicinal plants. Numerous investigations have shown that endophytes chemically produce secondary metabolites just like their hosts. Locals in Indian subcontinent and Southeast Asia have utilized Aegle marmelos for centuries to treat a variety of conditions, including dysentery, diarrhoea and dyspeptic symptoms. There have been numerous studies reporting the successful isolation of novel, beneficial bioactive compounds with antibiotic, anti-diabetic, antimicrobial and anti-cancer properties from endophytic fungi of this tree. The valuable bioactive chemicals produced by endophytic bacteria and actinomycetes have, however, received only a limited attention, making it a prime location for the discovery of new compounds for use in agricultural, and pharmaceutical industries. This review examines existing research data to reveal the biopotential of endophytes from Aegle marmelos as a promising source of naturally produced chemicals.