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Abstract

Drug Related Problems in Cardiovascular Diseases in Guntur, Andhra Pradesh

Author(s): Tulasi Uma Rani Nutakki*, D. K. Upadhaya and R. Akki
Department of Pharmacology, 1Department of Pharmacy, School of Pharmaceutical Sciences, Jaipur National University, Jaipur, Rajasthan 30217, 2Department of Pharmaceutics, Hindu College of Pharmacy, Guntur, Andhra Pradesh 5522007, India

Correspondence Address:
R. Akki, Department of Pharmaceutics, Hindu College of Pharmacy, Guntur, Andhra Pradesh 5522007, India, E-mail: nturani35@gmail.com


The present aim of our study was to assess drug related problems among patients with cardiovascular diseases. A prospective observational design was used to conduct this study. 1158 patients with cardiovascular are recruited in the study who visits the cardiology departments in Guntur. The classification of drug related problems was done by using the Pharmaceutical Care Network Europe drug related problem classification tool V9.1. A total of 743 drug-related problems were identified among 1158 patients, averaging 0.6 drug related problems per patient. The primary drug-related problem identified was in pulmonic closure treatment safety, with 60.1 % of adverse drug events possibly occurring. The most prevalent cause was drug selection, accounting for 71.19 %. During the study period, 148 adverse drug reactions were observed. On causality assessment, 41.89 % were classified as probable, 30.41 % as definite, and 27.7 % as possible. The most common adverse drug reactions encountered in this study were electrolyte imbalance, giddiness, headache, and cough (8.78 %). Treatment safety and drug selection were the major reasons for the development of drug related problems among patients with cardiovascular conditions. Majority of the adverse drug reactions are probable and mainly causing electrolyte imbalance.

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