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Abstract
Development and validation of spectrophotometric methods for the estimation of nitazoxanide in tablet dosage forms
Author(s): KV Lakshminarayana, YN Manohara, BM Gurupadayya
Department of Pharmaceutical Analysis, National College of Pharmacy, Balraj Urs Road, Shimoga-577 201, India
Correspondence Address:
Y N Manohara Department of Pharmaceutical Analysis, National College of Pharmacy, Shimoga-577 201 India E-mail: manoharayn@yahoo.com
Department of Pharmaceutical Analysis, National College of Pharmacy, Balraj Urs Road, Shimoga-577 201, India
Correspondence Address:
Y N Manohara Department of Pharmaceutical Analysis, National College of Pharmacy, Shimoga-577 201 India E-mail: manoharayn@yahoo.com
Two simple and sensitive visible spectrophotometric methods (A and B) have been developed for the quantitative estimation of nitazoxanide, in bulk drug and pharmaceutical dosage forms. Methods were based on the formation of reddish yellow coloured and green coloured chromogens, which were measured at 544 nm and 715 nm, respectively. The results obtained with the proposed methods are in good agreement with the labelled amounts when tablet dosage forms were analysed.
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