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Abstract
Determination of artemisinin in bulk and pharmaceutical dosage forms using HPTLC
Author(s): SP Agarwal, A Ali, Yashomati Dua, Shipra Ahuja
Department of Pharmaceutics, Faculty of Pharmacy, Jamia Hamdard University, New Delhi-110 062, India
Correspondence Address:
S P Agarwal Department of Pharmaceutics, Faculty of Pharmacy, Jamia Hamdard University, New Delhi-110 062 India agarwal_sp@yahoo.com
Department of Pharmaceutics, Faculty of Pharmacy, Jamia Hamdard University, New Delhi-110 062, India
Correspondence Address:
S P Agarwal Department of Pharmaceutics, Faculty of Pharmacy, Jamia Hamdard University, New Delhi-110 062 India agarwal_sp@yahoo.com
A new, simple, rapid, accurate and precise HPTLC method was developed. The detector response was linear for concentrations between 100-600 ng/spot (r =0.9931). The limits of detection and quantitation were 25 ng/spot and 75 ng/spot, respectively. The recovery study was carried out by standard addition method and was found to be 99.60±0.27. Statistical analysis proved that the method was precise, accurate and reproducible, and hence was suitable for the routine analysis of artemisinin.
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