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Abstract

Clinical Efficacy of Sodium Hyaluronate Eye Drops Combined With Pranoprofen in the Treatment of Patients with Dry Eye

Author(s): Guang Yang* and Ya Ming Wang
Department of Ophthalmology, Beijing Jishuitan Hospital, Changping, Beijing 100096, 1Department of Ophthalmology, Traditional Chinese medical hospital of Huangdao District, Qingdao, Shandong 266555, China

Correspondence Address:
Guang Yang, Department of Ophthalmology, Beijing Jishuitan Hospital, Changping, Beijing 100096, China, E-mail: ying156876156@163.com


To investigate the clinical efficacy of sodium hyaluronate eye drops combined with pranoprofen in the treatment of patients with dry eye. Total 72 patients with dry eye in our hospital from August 2019 to October 2019 were randomly divided into observation group and control group. In addition to the same basic treatment, the observation group used pranoprofen combined with sodium hyaluronate eye drops, while the control group only used sodium hyaluronate eye drops. The data changes of tear secretion test (Schirmer test) penetration length and tear film break-up time, quality of life and treatment effect were compared between the two groups. After treatment, the wet length of filter paper in the observation group was significantly longer than that in the control group. Comparing the time of tear film rupture before and after treatment, it was found that the time from blink to tear film rupture in the observation group was significantly longer than that in the observation group (p<0.05). In addition, the scores of physical function, physical pain, physical function, social function and mental health in the observation group were higher than those in the control group (p<0.05). Finally, the total effective rate of the treatment group was 100.00 % and that of the control group was 77.78 % (p<0.05). Pranoprofen combined with sodium hyaluronate has a very good effect in the treatment of dry eye after cataract surgery, which can increase the tear secretion, keep the eyeball moist, improve the stability of tear film and improve the quality of life of patients, which is worthy of wide application and promotion.

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