Abstract

The objective of this study was to determine the clinical value of medroxyprogesterone combined with different antibiotics in the treatment of chronic endometritis. A total of 320 subjects were selected and divided into study group and control group according to odd and even numbers, with 160 subjects in each group. The control group was treated with combination of antibiotics and the research group was given medroxyprogesterone on the basis of the control group. The medication cycle is 5 d. A comparative study was carried out on the effects of medication between the two groups. After medication, the total effective rate of patients in the study group was 94.37 %, significantly higher than 75.63 % in the control group (p<0.05). The levels of inflammation in both groups were reduced, but the research group was significantly better than the control group (p<0.05). The endometrial thickness and uterine recovery time in the study group were significantly better than those in the control group (p<0.05), while the sex hormone levels and irregular vaginal bleeding rate in the study group were significantly lower than those in the control group (p<0.05). The normal rate of menstruation and quality of life scores in the study group were significantly higher than those in the control group (p<0.05), and there was no significant difference in adverse drug reactions between the two groups (p>0.05). Progesterone combined with different antibiotics has a significant effect on chronic endometritis, which can reduce the level of inflammation, increase the thickness of endometrium, improve the level of uterine status and normal menstruation rate, reduce the level of sex hormones and the rate of irregular vaginal bleeding, etc. It has a good effect, high drug safety, helps to improve the quality of life and is worthy of popularization.