Abstract

To observe the efficacy and safety of Ertong Qingyan oral liquid in the treatment of herpes pharyngitis is the objective of this study. 151 children having herpes pharyngitis who were admitted to the department of pediatrics of Henan Provincial Children's Hospital from January 2021 to September 2022 were selected and were randomly divided into control group (n=75) and observation group (n=76). The control group was supplemented with interferon alpha 1b spray on the basis of conventional treatment, while the observation group was supplemented with interferon alpha 1b spray combined with Ertong Qingyan heat and toxin relieving oral liquid. The efficacy of the two groups was evaluated and comparing evaluating parameters after 5 d of the treatment. The total effective rate of the observation group was higher than that of the control group (94.7 % vs. 89.3 %) (p<0.05). The parameters such as time for body temperature to return to normal, the time for herpes to decrease, the time for salivary secretion to return to normal and the time for normal diet to start were better than that of the control group (p<0.05). Similarly, the levels of interleukin-7, interleukin-10 and tumor necrosis factor alpha were significantly lower than that of the pre-treatment group and the control group (p<0.05). The levels of immunoglobins A, G and M in the observation group were significantly higher than those in the control group after treatment (p<0.05). No adverse reactions occurred during the treatment period. Finally it can be concluded that Ertong Qingyan oral solution is effective and safe in the treatment of herpes pharyngitis in children.