All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.
Abstract
Antitumour Activity Of Biochanin-A Against Dalton's Ascitic Lymphoma
Author(s): S Kavimani, R Ilango, N. S Nagarajan, C Manoj, Malaya Gupta, U. K Majumdar
The antitumour activity of biochanin-A (5,7-dihydroxy-4-methoxy isoflavone) has been evaluated against Dalton's ascitic lymphoma (DAL) in swiss albino mice. A significant enhancement of mean survival time of biochanin-A treated tumour bearing mice was found with respect to control group. Biochanin-A treatment was found to enhance peritoneal cell counts. When these biochanin-A treated animals underwent i.p. inoculation with DAL cells, tumour cell growth was found to be Inhibited. After 14 days of inoculation, biochanin-A is able to, reverse the changes in the haematological parameters, protein and PCV consequent to tumour inoculation.
PDF
