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Abstract
A new spectrophotometric method for the estimation of primaquine using MBTH
Author(s): BS Sastry, EV Rao, MK Tumuru, C SP Sastry
Dept. of Pharmaceutical Sciences and Foods and Drugs Laboratory, Dept. of Chemistry, Andhra University, Waltair 530 003
Correspondence Address:
B S Sastry Dept. of Pharmaceutical Sciences and Foods and Drugs Laboratory, Dept. of Chemistry, Andhra University, Waltair 530 003
Dept. of Pharmaceutical Sciences and Foods and Drugs Laboratory, Dept. of Chemistry, Andhra University, Waltair 530 003
Correspondence Address:
B S Sastry Dept. of Pharmaceutical Sciences and Foods and Drugs Laboratory, Dept. of Chemistry, Andhra University, Waltair 530 003
A spectrophotometric method for the determination of primaquine at 510 nm, based on its reaction with 3-methyl-2-benzothiazolinone hydrazone (MBTH) in the presence of cerium (IV) to form a stable, pink coloured oxidative coupling product, is reported. The method is applicable in the presence of other antimalarial drugs and to pharmaceutical preparation
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