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Abstract
A new spectrophotometric determination of famotidine from tablets
Author(s): N Rami Reddy1, K Prabhavathi1, YV Bhaskar Reddy2, IE Chakravarthy3
1 Department of Chemistry, S. B. S. Y. M. Degree College, Kurnool-518 004, India 2 Department of Pharmacology, Government Medical College, Kurnool-518 002, India 3 Department of Chemistry, S. K. U. P. G. Centre, Kurnool-518 002, India
Correspondence Address:
I E Chakravarthy Department of Chemistry, S. B. S. Y. M. Degree College, Kurnool-518 004 India E-mail: ramireddy_m2000@yahoo.co.in
1 Department of Chemistry, S. B. S. Y. M. Degree College, Kurnool-518 004, India 2 Department of Pharmacology, Government Medical College, Kurnool-518 002, India 3 Department of Chemistry, S. K. U. P. G. Centre, Kurnool-518 002, India
Correspondence Address:
I E Chakravarthy Department of Chemistry, S. B. S. Y. M. Degree College, Kurnool-518 004 India E-mail: ramireddy_m2000@yahoo.co.in
A simple spectrophotometric method for determination of famotidine was described. The method was based on bromination of the drug with excess brominating mixture in acidic medium. The yellow colour developed was measured at 350 nm against distilled water blank. Beer's law was obeyed in the range of 40-200 µg/ml.
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