Abstract
A Meta-Analysis of Influencing Factors of Drug Therapy Compliance in Chinese Children with Bronchial Asthma
Operating Room Department, 1Division of Paediatric Gastroenterology, West China School of Nursing/West China Second University Hospital, Sichuan University, Chengdu, Sichuan 610041, 2Department of Epidemiology and Biostatistics, School of Public Health, Xi’an Jiaotong University Health Science Centre, Xi'an, Shaanxi 710061, 3Department of Paediatric Nursing, West China School of Nursing/West China Second University Hospital, Sichuan University, Chengdu, Sichuan 610041, 4Department of Paediatrics, Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, Chengdu, Sichuan 610041, China
Correspondence Address:
Qin Zeng, Division of Paediatric Gastroenterology, West China School of Nursing/West China Second University Hospital, Sichuan University, Chengdu, Sichuan 610041, China, E-mail: zeng212212@163.com
We systematically attempt to evaluate the influencing factors of drug treatment compliance in childhood asthma and to provide evidence for improving patient’s treatment compliance and improving treatment success rate. The Chinese literatures that met the inclusion and exclusion criteria, such as Wanfang Medical Database, China National Knowledge Infrastructure, VIP Chinese Science and Technology Periodical Database and Chinese Biomedical Database were systematically searched. Two researchers screened the literature, conducted strict quality evaluation, extracted data from literatures that met the quality standards and used RevMan5.3 statistical software to make forest charts for outcome indicators and analyze effects. A total of 13 literatures were included. Meta-analysis results showed that lack of asthma knowledge, bad psychology and parent’s trust in medical staff had no statistically significant effects on children’s treatment compliance, while the degree of illness had a statistically significant impact on compliance (p<0.1), the pooled odds ratio and 95 % confidence interval was 0.31 (0.22-0.43). The severity of illness is the main factor for drug treatment compliance in childhood asthma.
