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Abstract
3-Substituted lawsones and their calcium and zinc chelates as antimicrobials
Author(s): VD Kelkar, BM Rawal, PL Kulkarni, Pl Kulkarni
Dept. of Chemistry, University of Poona, Pune 411 007,
Correspondence Address:
V D Kelkar Dept. of Chemistry, University of Poona, Pune 411 007
Dept. of Chemistry, University of Poona, Pune 411 007,
Correspondence Address:
V D Kelkar Dept. of Chemistry, University of Poona, Pune 411 007
Antimicrobial studies of lowsone and six derivatives along with their chelates with calsium and zinc are carried out by disc assay method. All the chelates have ML2 2H2O composition and possibly trans-octahedral structure. Due to substituent at C-3 the antibacterial activity decreases and the antifungal activity increases. Chelate-formation lowers antimicrobial activity.
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